The Syrian American Council is one of the largest American based Syrian lobbying organizations and key SAC leaders are tied to the Muslim Brotherhood in the US:
- The last known SAC President was Talal Sunbulli (aka Talal Sunulle ) who was listed as the Syrian coordinator in the international phone book of Muslim Brotherhood members seized by federal investigators during the Holy Land Foundation investigation.
- The last known SAC Chairman was Hussam Ayloush, Executive Director of the California office of the Council on American Islamic Relations (CAIR), a part of the Us Muslim Brotherhood.
- US Muslim Brotherhood figure Louay Safi is known to have been a leading member.